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Undergraduate Courses

BI3124 / BI6114 (earlier BIO 313)

ADVANCED MOLECULAR BIOLOGY

4 CREDITS

Fall Semester

 

Introduction:

This course will provide fundamental concepts from this enormous and ever-growing field of Molecular Biology to Undergraduate students. This course will help students to have a sound knowledge of molecular biology, which will also enable them to carry out research using molecular biology techniques.

 

Content:

This course covers a detailed analysis of the molecular mechanisms that control the maintenance, expression, and evolution of prokaryotic and eukaryotic genomes. The topics covered in lectures and readings of relevant literature include maintenance and expression of the genome including DNA replication, mutability and repair of DNA, genetic recombination, gene regulation, transcription, RNA splicing and translation. In particular, the logic of experimental design and data analysis is emphasized in particular molecular cloning methods and tools for studying gene and gene activity.

 

 

Recommended Readings:

1) Molecular Biology of the Gene by Watson, Baker, Levine, Losick et al. [2007] 6 Ed. Benjamin Cummings

2) Molecular Biology by Weaver [2011] 5 Ed. McGraw-Hill Science

3) Principles of Gene Manipulation by Primrose, Twyman, Old [2002] 6 Ed. Wiley-Blackwell

4) Molecular Biology and Genomics by Mulhardt [2006] 1 Ed. Elsevier

 

Prerequisite: None.

BIO 463/650

BIOLOGY AND DISEASE

4 CREDITS 

Spring Semester

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Introduction: Integrate the biology (cell, molecular and physiology) taught so far, 2) develop insights into biology revealed by the disease condition, and 3) teach technology development and translation prompted by the disease condition. Cancer, neurodegenerative disorders, infectious diseases, disorder of the cardiovascular system and genetic diseases will be used studied.

 

Content:

What is Cancer and profile of a cancer cell; causes of cancer and how it spreads; molecular biology of cancer; What is neurodegeneration and biology of the disease; molecular basis of neurodegenerative disorders; Major types of heart diseases and their causes; review some of the methods for detecting and investigating heart disease; How genetic traits are inherited; effects of single gene mutations; types of chromosomal mutations; ways in which single gene mutations are treated; Types and symptoms of some common infectious diseases; outline preventive measures; general effects of antibiotics on infectious organisms, discuss some general aspects of the management and treatment of specific infectious diseases.

 

Recommended readings:

1)  Biology of Disease by Nessar Ahmed, Maureen Dawson, Chris Smith and Ed Wood; Taylor & Francis; 1 edition (December 13, 2006)

2) One Renegade Cell: The Quest For The Origin Of Cancer (Science Masters) by Robert A. Weinberg; Basic Books; 1 edition (October 7, 1999)

3) The Biology of Cancer by Robert Weinberg; Garland Science; 1 edition (June 7, 2006)

4) The Biology Of Disease by Murray, Jonathan and Kirk; Wiley-blackwell; 2 edition [May 2001]

 

Prerequisite: BI3124 / BI6114  [Advanced Molecular Biology]

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